In the landscape of modern aesthetic medicine, few innovations have generated as much excitement as Exosomes, extracellular particles capable of communicating directly with cells, stimulating deep regeneration.
If we add the effectiveness of microneedling to this cutting-edge technology, we get one of the most powerful and advanced treatments currently available to visibly improve skin quality: ASCEplus SRLV, the new generation exosome used today in highly effective professional protocols.

In this article, we will explore in detail what Asce Plus is, why it is considered the regenerative therapy of the future, how it works in combination with microneedling, and what results can be achieved from the very first sessions.

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🔬 What is ASCEplus SRLV?

ASCEplus is the world’s first professional plant-based exosome, obtained thanks to the patented technology ExoSCRT®, a highly selective process that isolates only pure exosomes from 0.1% to 0.5% of the cell medium, ensuring maximum product efficacy and stability.

This is an Advanced Exosome Complex, designed exclusively for medical and professional aesthetic use. Each kit contains:

• Vial 1 – Lyophilized Powder with exosomes, growth factors, peptides, amino acids, vitamins, and minerals

• Vial 2 – Diluent based on high molecular weight hyaluronic acid, growth factors, and amino acids

As reported in the official brochure, each package contains 5 billion exosomes (20 mg + 5 ml) per vial, designed for intensive skin treatments.

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🌹 Why specifically the Damask Rose?

ASCEplus exosomes derive from Damask Rose plant stem cells, selected because:

• they have shape and size very similar to those of human stem cells

• they are rich in active microRNAs, 27 of which have human matches

• they promote cell proliferation, including that of fibroblasts

• they increase collagen and elastin production

• they reduce melanin and skin inflammation

This information, taken from the official ASCEplus documentation, confirms the highly regenerative profile of plant exosomes and their high biocompatibility.

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💎 The scientifically proven benefits of ASCEplus Exosomes

The ExoSCRT® exosomal technology offers quantifiable skin improvements, as indicated in the official materials:

✔ Increase of Collagen up to +690%

✔ Increase of Elastin up to +300%

✔ Reduction of Melanin up to -75%

These data — reported in the ASCEplus medical brochure — show why exosomes are today one of the most powerful anti-aging and depigmenting tools.

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🔎 How do exosomes work in the skin?

Exosomes act as true “smart messengers”: they carry biological information from one cell to another to stimulate:

• tissue regeneration and repair

• fibroblast proliferation

• synthesis of collagen, elastin, and extracellular matrix

• reduction of inflammation

• restoration of the skin barrier

• normalization of cell turnover

In other words, they teach the skin to regenerate faster and more effectively.

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🔥 Microneedling: the perfect technology to deliver exosomes

Microneedling is a minimally invasive treatment that creates uniform micro-channels in the dermis. These micro-perforations:

• they alone stimulate collagen production

• they increase skin permeability

• they allow ASCEplus exosomes to penetrate deeper

• they accelerate the regenerative response

When microneedling and exosomes are combined, the effects are multiplied.

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💠 Official ASCEplus Protocols: what happens during a treatment?

According to the ASCEplus protocol manual (July 2025), the treatment is structured in precise steps:

1. Professional cleansing

The skin is cleaned and prepared for absorption⁠—Step 1 of the official protocol.

2. Application of anesthetic cream

To ensure maximum comfort during microneedling—Step 2 of the protocol.

3. Microneedling Treatment

It is performed until the desired end point, following professional guidelines⁠—Step 3.

4. Application of ASCEplus SRLV

Exosomes are applied immediately afterward, when the skin is most receptive⁠—Step 4.

5. Improved absorption (LED or sonophoresis)

Optional techniques that enhance active ingredient penetration.

6. ASCEplus soothing mask

To soothe and hydrate the skin—Step 6.

7. Post-treatment advice

Sun protection and targeted home care—Step 7.

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🕒 How many sessions are needed?

Official protocols recommend:

• 3–5 treatments spaced 2 weeks apart in intensive cycles

• 1 treatment per month to consolidate results

• maintenance every 6–12 months

Improvements are individual and visible already after 2–3 days according to SRLV protocols.

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✨ The aesthetic benefits of Microneedling with ASCE Plus Exosomes

1️⃣ Overall facial rejuvenation

The skin appears firmer, more elastic, and radiant thanks to increased collagen and elastin.

2️⃣ Reduction of wrinkles and fine lines

The dermis plumps from within, with a natural smoothing effect.

3️⃣ Lightening of spots and hyperpigmentation

ASCE exosomes reduce melanin by up to 75%, improving discolorations and post-inflammatory spots.

4️⃣ Improvement of acne scars

The combined action of microneedling + exosomes promotes the remodeling of scar tissue.

5️⃣ Reduction of enlarged pores and uneven texture

The skin appears firmer and more even.

6️⃣ Immediate anti-inflammatory effect

Thanks to PRDX proteins and Let-7b microRNAs present in exosomes (page 2 of the brochure), the skin becomes more balanced and less reactive.

7️⃣ Skin barrier repair

The skin becomes more resilient, hydrated, and healthy.

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🌈 Who is the treatment indicated for?

The treatment is ideal for those who want:

• tired, dull, and dehydrated skin

• expression wrinkles or early signs of aging

• discolorations, spots, melasma

• post-acne scars

• enlarged pores

• sensitive skin prone to inflammation

• improvement of the overall skin quality

It is a treatment suitable for both women and men of all ages.

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⚠️ Contraindications

• pregnancy/breastfeeding

• active infections or dermatitis

• recent isotretinoin intake

• open wounds or significant irritations

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💡 Why choose a treatment with ASCEplus exosomes over traditional microneedling?

ASCEplus SRLV takes microneedling to the next level, becoming a complete deep regeneration treatment.

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💬 Results: what to expect

After 24–48 hours the skin appears:

• brighter

• more compact

• more hydrated

After 1–2 weeks:

• visible reduction of wrinkles

• less visible pores

• smoother scars

• lighter spots

After a complete cycle:

• overall facial rejuvenation

• stronger, healthier, and more even skin

• improvement in texture and tone

• stable and lasting results

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🌟 Conclusion: the future of skincare is here

Microneedling with ASCEplus Exosomes is not just a cosmetic treatment: it is true cellular regeneration that uses intercellular communication to stimulate the skin from within.

Thanks to:

✔ ExoSCRT® technology
✔ Damascus Rose exosomes
✔ certified professional protocols
✔ clinically proven results

ASCEplus SRLV today represents one of the most advanced solutions for facial rejuvenation and correction of skin imperfections.

A complete, safe, biocompatible, and extraordinarily effective treatment.